Urine proteomic profiling of pediatric nephrotic syndrome
نویسندگان
چکیده
منابع مشابه
Examine of Thyroid Function in Pediatric Nephrotic Syndrome; Tehran-Iran
Introduction In children with nephrotic syndrome, it is probable to determine a hypothyroid state because of thyroxine (T4), tri-iodothyronine (T3) and thyroid-binding globulin loss in presence of proteinuria. Objectives: To examine thyroid function in pediatric cases of nephrotic syndrome. Methods: In a cross-sectional study, from march 2010 to march 2012, thyroid function tests were performed...
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Several days after unprotected sex, a 21-year-old male was referred with generalized edema and enlarged painless lymph nodes. Urinalysis showed specific gravity 1036, proteinuria 4+, nitrites negative, urine microscopy with 4–6 erythrocytes/high power field (HPF), 8–10 leucocytes/HPF and the presence of hyaline and granular casts. Urine culture was negative. Proteinuria was 4.6 g/24 h, serum cr...
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BACKGROUND & OBJECTIVES At present, the diagnosis of nephrotic syndrome (NS) requires a renal biopsy which is an invasive procedure. We undertook this pilot study to develop an alternative method and potential new biomarkers for diagnosis, and validated a set of well-integrated tools called ClinProt to investigate serum petidome in NS patients. METHODS The fasting blood samples from 49 patien...
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Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the first line of treatment. A significant number of patients with SRNS progress to end-stage renal disease if remission is not achieved. For these chi...
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We used protein expression profiles to develop a classification rule for the detection and prognostic assessment of bladder cancer in voided urine samples. Using the Ciphergen PBS II ProteinChip Reader, we analyzed the protein profiles of 18 pairs of samples of bladder tumor and adjacent urothelium tissue, a training set of 85 voided urine samples (32 controls and 53 bladder cancer), and a blin...
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ژورنال
عنوان ژورنال: Pediatric Nephrology
سال: 2006
ISSN: 0931-041X,1432-198X
DOI: 10.1007/s00467-006-0165-8